By "fatigue", I mean the experience of exhaustion, typically from a depletion of usable energy.
By "cosmic universal", I mean the aspect of reality that is shared by all parts and pieces of reality.
Humans experience fatigue all the time - we cannot run a marathon without feeling physically fatigued at the end, we cannot work a twelve hour shift without feeling mentally fatigued, we cannot contemplate the human condition without feeling disenchanted, disoriented, and overall fatigued (i.e. Weltschmerz). We have to sleep 8+ hours a day in order to not feel fatigued before our day is done. To sleep is to re-charge for yet another day.
Similarly, and perhaps metaphorically, everything else experience fatigue. The steel beams in which an architectural structure rests upon will experience fatigue eventually, and will snap. A chemical reaction will experience fatigue when it runs out of reactive material. The wave along the beach reaches a crest and then violently splashes down on the sand before dissipating into a more restful state - the wave has fatigued.
Perhaps "fatigue" is not the most scientific term - perhaps we ought to use "entropy". From an objective stance, entropification is the cosmic universal. But from a subjective, phenomenological stance, fatigue is the cosmic universal.
Entropification, or fatigue, cannot be achieved without process. Staticity is impossible, except for perhaps the conditions of existence "simpliciter" and the final end state of a process.
And so fatigue is the final resolution of any process. We can then say that any process is the process of fatigue - processes are described by their ends to which they point, therefore fatigueis process. To be a process means to fatigue.